Objective To improve the surface hardness and wear resistance of titanium alloy. Methods An experimental research of 80% CBN+20% Ti coating was prepared on TC11 alloy surface using laser cladding technology. The microstructure, hardness and wear resistance of the clad coating were analyzed. Results Microstructure analyses showed that the clad coating could be divided into three zones along the depth direction: clad, binding and transition zones, and there were no obvious cracks and faults among the zones. The maximal microhardness of the CBN membrane layer reached 950HV0. 2, and the wear resistance performance of CBN anti-wear coating was nearly 14 times as high as that of pure Ti coating. Conclusion The wear resistance performance of CBN laser clad anti-wear coating on titanium alloy surface was good, and the surface hardness of the titanium alloy was effectively improved.