Research Progress on Surface Treatment Technology of Medical Titanium Alloys

TAN Rongkai, LIU Hongfeng, BAO Lin, ZHANG Liusheng, YANG Shide, SHU Shengrong, LI Guanlin

Surface Technology ›› 2026, Vol. 55 ›› Issue (20) : 201-228.

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Surface Technology ›› 2026, Vol. 55 ›› Issue (20) : 201-228. DOI: 10.16490/j.cnki.issn.1001-3660.2026.20.015
Functional Surfaces and Technology

Research Progress on Surface Treatment Technology of Medical Titanium Alloys

  • TAN Rongkai1,*, LIU Hongfeng1, BAO Lin2, ZHANG Liusheng1, YANG Shide1, SHU Shengrong1, LI Guanlin1
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Abstract

Medical titanium alloys have become essential materials for orthopedic and dental implants thanks to their excellent specific strength, biocompatibility, and corrosion resistance. However, when deployed in complex physiological environments for extended periods, these implants encounter multiple challenges, including friction and wear, corrosion failure, fatigue damage, insufficient osseointegration, and bacterial infection, that severely restrict their long-term stability and service life. To address these problems, surface treatment technologies have emerged as one of the most effective methods to improve the comprehensive service performance of titanium alloys by precisely controlling the morphology, composition, and structure of the material surface layer. This article focuses on orthopedic load-bearing implants (artificial joints, bone plates and screws, and dental implants) and systematically reviews three major categories of surface modification techniques.
Surface texturing technologies, such as laser surface texturing, chemical etching, and sandblasting, construct micro- and nano-scale morphologies on the surface. Laser surface texturing, particularly ultra-short pulse laser processing, can fabricate high-precision, designable micro-grooves or micro-pit arrays within a minimal heat-affected zone. These structures provide physical anchorage sites for cell adhesion, promote osteoblast differentiation, and simultaneously function as lubricant reservoirs and debris traps at the friction interface, reducing the friction coefficient and wear rate by 55%-90%. Chemical etching uses acid or alkali solutions to create uniform micro-nano porous structures, substantially enhancing biological activity with mineralization capacity improved by up to 230%. Sandblasting combined with acid etching (SLA) can further improve bioactivity and antibacterial ability. The key advantage lies in achieving multifunctional synergy of friction reduction, osseointegration promotion, and antibacterial performance through geometric design without altering the bulk composition.
Surface coating technologies, including physical vapor deposition (PVD), micro-arc oxidation (MAO), and plasma spraying, deposit functional layers onto the substrate, directly endowing the surface with new properties. PVD can produce dense, high-hardness coatings such as zirconium nitride and titanium nitride, delivering hardness improvements of up to 91%. MAO forms a firmly adherent, porous TiO2-based ceramic layer that simultaneously incorporates bioactive or antibacterial elements such as calcium, phosphorus, silver, and zinc, reducing the friction coefficient to as low as 0.2. Plasma spraying is commonly used to deposit hydroxyapatite coatings for bone tissue ingrowth, and tantalum coatings prepared by this method exhibit particularly outstanding comprehensive performance. The advantage of surface coating lies in directly imparting wear resistance, corrosion resistance, and bioactivity to the implant surface.
Surface microstructure strengthening technologies, including laser shock peening (LSP), shot peening (SP), and ion implantation, fundamentally enhance material performance by introducing residual compressive stress and refining surface grains. LSP generates a deep compressive stress field reaching several hundred micrometers, significantly improving the fatigue life by nearly threefold and reducing the corrosion current density fourfold. SP combined with plasma nitriding can reduce the wear rate by up to 98%. Ion implantation enables precise doping of functional elements such as N for hardness, Cu and Ag for antibacterial performance, and Ta and Zr for corrosion resistance, while maintaining a metallurgical bond between the modified layer and the substrate.
Despite significant progress in this field, a critical underlying challenge remains: the desired functions do not always reinforce one another. High surface roughness or porous structures that promote cell adhesion and bone ingrowth may simultaneously create favorable sites for bacterial colonization. For doped antibacterial ions, the effective concentration operates within a narrow safety window relative to cytotoxicity. The densification of coatings beneficial for corrosion resistance may compromise bioactivity, just as higher porosity enhances bone ingrowth at the expense of corrosion protection. Therefore, future development should identify optimal parameter windows that achieve dynamic multifunctional balance. Key trends include multi-field coupled hybrid processes, intelligent parameter optimization driven by machine learning, environmentally benign surface chemistries, and rigorous long-term in vivo validation to bridge the gap between laboratory research and clinical translation. The differentiated requirements for distinct implant types further underscore the need for application-specific design strategies, including wear-resistant coatings with deep strengthening for artificial joints, fatigue resistance with osteogenic bioactivity for bone plates and screws, and antibacterial function with early osseointegration for dental implants.

Key words

medical titanium alloy / surface treatment technologies / surface texture / surface coating / surface tissue strengthening

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TAN Rongkai, LIU Hongfeng, BAO Lin, ZHANG Liusheng, YANG Shide, SHU Shengrong, LI Guanlin. Research Progress on Surface Treatment Technology of Medical Titanium Alloys[J]. Surface Technology. 2026, 55(20): 201-228

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Funding

National Natural Science Foundation of China (52565050); Jiangxi Provincial Natural Science Foundation (20232BAB214056)
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