The negative impact of traditional mineral oil based grinding fluids on environmental protection, human health and manufacturing costs can hardly meet the development needs of green manufacturing. Minimum quantity lubrication (MQL) atomizes a small amount of biodegradable biolubricants with compressed air to form micro droplets to providing lubrication and anti-wear effects, which is an ideal alternative to flooding and dry grinding technology defects. In order to meet the requirements of anti-wear and friction reduction and enhanced heat transfer in the grinding zone under high temperature and high pressure boundary conditions, nanobiolubricants have been widely investigated as atomised media for minimum quantity lubrication. However, the application of nanobiolubricants as cooling and lubrication media in grinding still faces serious challenges due to the unclear mapping relationship between the physicochemical properties of nanobiolubricants and grinding performance. This is due to the fact that the mechanisms of action of nanoparticles on lubricants is a result of multiple coupling factors. Nanoparticles will not only improve the heat transfer and tribological properties of biological lubricants, but also increase their viscosity. However, the coupling mechanisms between the two factors are often be overlooked. In addition, as a cooling and lubrication medium, the compatibility between nanobiolubricants with different physical and chemical properties and workpiece materials also needs to be further summarized and evaluated. To address these needs, this paper presents a comprehensive assessment of the grinding performance of nanobiolubricants based on tribology, heat transfer and workpiece surface integrity. Firstly, the physicochemical properties of nanobiolubricants were described from the perspectives of base fluids and nano additive phase. And factors which influenced thermophysical properties of nanobiolubricants were analysed. Secondly, the excellent grinding performance of the nanobiolubricants was analysed in relation to their unique film-forming and heat transfer capabilities. Coolingand lubrication mechanism of nanobiolubricants in grinding process was revealed. The results showed that nanobiolubricants can be used as a high-performance cooling lubricant under the trend of reducing the supply of grinding fluids. The excellent heat transfer and extreme pressure film-forming properties of nanobiolubricants significantly improved the extreme friction conditions in the grinding zone, and the surface roughness values (Ra) could be reduced by about 10%-22.4%, grinding temperatures could be reduced by about 13%-36% compared with the traditional minimum quantity lubrication. Furtherly, the multi-field endowment modulation strategy was investigated to elucidate the mechanism of nanobiolubricant infiltration and heat transfer enhancement in the multi-field endowed grinding zone. Multiple fields such as magnetic and ultrasonic fields have improved the wetting performance of nanobiolubricant droplets, effectively avoiding the thermal damage and enabling the replacement of flood lubrication. In the grinding of hard and brittle materials, ultrasonic energy not only enhances the penetration of the grinding fluid through the pumping effect, but also reduces the brittle fracture of the material, and the surface roughness value (Ra) can be reduced by about 10%-15.7% compared with the traditional minimum quantity lubrication. Finally, an outlook for engineering and scientific bottleneck of nanobiolubricants was presented to provide theoretical guidance and technical support for the industrial application and scientific research of nanobiolubricants.