In order to explore the new technology of high-efficiency and high-quality surface strengthening and modification of offshore engineering equipment, and improve the preparation efficiency and comprehensive performance of 17-4PH stainless steel layer. Three cladding layers of 17-4PH wire, 17-4PH wire with B4C powder and 17-4PH wire with Cr3C2 powder were prepared by high-speed laser cladding technology. The microstructure of the cladding layer was analyzed by X-ray diffraction, scanning electron microscope and energy dispersive spectrometer. The hardness and corrosion resistance of the cladding layer were tested by microhardness tester and electrochemical workstation. The results show that the cladding layer of 17-4PH wire is mainly α phase (martensite), and the two kinds of silk powder cooperate with the phase structure of the cladding layer α in addition to phase (martensite), it also appears γ phase (austenite); The microstructure and composition of the three cladding layers are uniform as a whole. Carbide precipitation such as Cr and Nb appears at the grain boundary of the wire powder cooperative cladding layer, and carbide particles are distributed on the surface layer; The addition of carbide particles improves the hardness of the cladding layer, especially the addition of B4C particles. It not only acts as a hard phase reinforced cladding layer to uniformly refine the grains, but also precipitates a large number of second phase particles at the grain boundary and in the crystal. The hardness is about 35.53% higher than that of the 17-4PH wire cladding layer without carbide particles; The corrosion resistance of the three cladding layers in 3.5wt.%NaCl solution is good, especially the cladding layer with Cr3C2 particles added together. Compared with the 17-4PH wire cladding layer, the corrosion current density is 0.592 400 μA/cm2 reduced to 0.014 094 μA/cm2, the corrosion potential increased from –0.314 05 V to –0.134 64 V. In this paper, the stainless steel layer is prepared with high efficiency and high quality with the co preheated welding wire and coaxial powder at the cladding speed of 40 mm/s, which fully combines the advantages of high hot wire cladding efficiency and easy adjustment of powder feeding cladding composition; Compared with the 17-4PH wire cladding layer, the phases of the two silk powder cooperative cladding layers are eliminated α out of phase γ. The addition of carbide refines the structure, and there are new precipitates at the grain boundary; The hardness of 17-4PH wire and B4C powder cladding layer is significantly improved, while the corrosion resistance of 17-4PH wire and Cr3C2 powder cladding layer in 3.5wt.% NaCl solution is significantly improved.