This study aims to investigate the influence of rules and actual surface profile on the two-dimensional line contact model. The present study develops a numerical line contact model based on the geometric characteristics of line contact, and the surface deformation along with the surface roughness are taken into account. A moving average filter is used to smooth the actual rough surface to consider the running-in process, and the conjugate gradient method is adopted to solve the surface contact pressure and friction. The near-field stresses distribution in two-dimensional plane are calculated based on the discrete convolution fast Fourier transform method to improve calculation efficiency. First, the accuracy of two-dimensional contact model is verified by comparison. Then, the stress distribution and magnitude in the plane stress distribution cloud diagram are compared when the regular and actual rough topographic surfaces are subjected to normal load and tangential load. The maximum Mises stress increases when the radius of the circular asperity decreases. Multiple circular asperities and sinusoidal asperities have similar effects on stress distribution. When the tangential force is considered, it will have significant effects on the shape and size of the stress distribution. For the same surface topography, the greater the friction coefficient is, the greater the Mises stress is, and the stress shifts along the direction of the frictional force. The numerical model in this paper can accurately calculate the stress near the rough surface. When the cylinder surface is in contact with a rough surface, the stress distribution is changed significantly compared to the smooth surface contact. The smaller the asperity scale is, the more concentrated the stresses are; the friction will shift the contact pressure and the near-field Mises stress along the direction of the friction. The larger the friction coefficient, the more obvious the shift; when considering the actual rough surface, stress concentration occurs around the roughness peaks with level of amplitude; the stress concentration surrounding roughness peaks will be greatly reduced after the average filter smoothing treatment when surface running-in effects are considered.