In order to solve the problem that the service life of surface layer of stainless steel parts is shortened due to wear and corrosion in engineering practice, efforts are made to repair and improve the hardness, wear resistance and corrosion resistance of surface layer of stainless steel. On the basis of summarizing a lot of experimental data and rules in the early stage, Ni60 coating with good cladding quality and no cracks was prepared on 304 stainless steel surface by laser cladding. The microstructure, element distribution and phase structure of the cladding surface were systematically studied by optical microscope, scanning electron microscope, energy dispersive spectrometer and X-ray diffractometer. The hardness distribution, wear characteristics and electrochemical characteristics of the cladding surface were measured by microhardness tester, friction and wear tester and electrochemical workstation. The uniform and compact microstructure of the coating is mainly composed of solid solution state γ-(Ni,Fe), carbides M23C6 (M=Fe, Ni, Cr) and boride CrB. The microhardness of the cladding coating is about 2.5 times that of the substrate. The hardness enhancement of the coating is mainly caused by the hard reinforcing phase formed in the cladding process. The wear rate, wear depth and wear surface roughness per unit area (Sa) of the cladding coating are 8.5%, 69% and 22.2% of the substrate, respectively. Compared with the substrate, the wear resistance of the cladding coating is obviously better. The corrosion rate of the coating is 2 orders of magnitude lower than that of the substrate, and the formation of dense passivation film on the coating surface is the main reason for the good corrosion resistance. Compared with 304 austenitic stainless steel base material, Ni60 coating with good cladding quality has better hardness, wear resistance and corrosion resistance.