This work investigated the microstructure, corrosion and wear resistance and corrosion mechanism of Ni60 and Ni60WC spray welding coating, which can provide a reference for the selection of spray welding coating for the mechanical parts in service under severe working environment. Ni60 and Ni60WC coatings were prepared on 16Mn steel substrate by an oxy-acetylene flame spray welding process. The phase composition and microstructure of the coatings were tested and analyzed by an X-ray diffractometer, metallographic microscope and scanning electron microscope. The corrosion and wear resistance of the two coatings were studied by an electrochemical workstation, salt spray(fog) apparatus and abrasive wear tester. The results show that there are metallurgical bonding layer and heat affected zone between spray welding layer and 16Mn steel substrate. The microstructure of the Ni60 coating is a large number of smaller-sized granular and rod-shaped carbides and borides dispersed on the NiCr solid solution substrate. In addition to the fine hard phase similar to the Ni60 coating, the Ni60WC spray-welded coating has a uniform distribution of WC particles of different sizes. The wear rates of Ni60 and Ni60WC coating are 8.3% and 2.3% of 16Mn steel respectively, and the self-corrosion current densities are 1.0% and 7.6% of 16Mn steel respectively. In addition, the galvanic corrosion between the matrix phase and the hard phase is the main corrosion mechanism of the two nickel based spray welding coatings. Both Ni60 and Ni60WC spray welding coatings can significantly improve the wear and corrosion resistance of the 16Mn steel. Among them, Ni60 and Ni60WC coatings are respectively suitable for surface protection of mechanical parts in service environment where corrosion and wear are the main factors.