This paper summarized the preparation methods of micro-arc oxidation biofilm on titanium alloy at home and abroad, and mainly elaborated the influence mechanism of electrical parameters and electrolyte on the structure and performance of micro-arc oxidation biofilm on titanium alloy. The current under the pulse power supply had a good adjustment effect on the preparation of the film, and the thickness of the obtained film was significantly increased. When the film thickness increased with the increased of the oxidation voltage, the color of the film surface and the corrosion potential also changed. When the pulse width was increased and the frequency was decreased, the single pulse discharge energy was increased, and the film formation rate of micro-arc oxidation was significantly accelerated. There are differences in the surface roughness and microporous structure of membranes prepared from different electrolyte systems. The introduction of silver, zinc, and copper ions into the electrolyte can effectively improve the problem of foreign body inflammation caused by bacterial adhesion on the surface of the implant coating, thereby enhancing its antibacterial effect. Based on the current research progress of titanium alloy micro-arc oxidation, this research direction was prospected, and it had a positive role in promoting the development of titanium alloy implants in clinical medical applications.