In recent years, with the continuous development of modern industry, the applications of metal materials are becoming more and more extensive. At the same time, the corrosion of metal materials is also widely concerned. Superhydrophobic compounds are used in the field of metal corrosion protection because of their excellent chemical properties. In this paper, the principle of superhydrophobic compounds protection on metal substrate are introduced, and the methods of preparing superhydrophobic surface commonly used in recent years are summarized. For example, the compounds with low surface energy are modified by fluorides, stearic acids, long-chain alkyls or silyl group to build superhydrophobic surface with low surface energy. Superhydrophobic compounds, organic metal framework compounds (MOFs), corrosion inhibitors and microcapsules can protect the metal matrix through synergistic action:(1) Some hydrophobic compounds are used to modify the organic MOFs with special surface properties to produce superhydrophobic surfaces; (2) The inhibitors are modified by some long-chain hydrophobic compounds to improve their hydrophobicity so as to obtain the better anticorrosion effect; (3) Microcapsules with self-healing function and hydrophobic compounds can exhibit the best anti-corrosion performance through synergistic action. The applications of superhydrophobic compounds in metal corrosion and protection are prospected.