The work aims to explore the influence of glass deposits CMAS (CaO-MgO-Al2O3-SiO2) on the thermal shock life of the new structure thermal barrier coatings (TBCs) at 1250 ℃ and reveal the failure behavior of these coatings. CMAS powder was uniformly deposited on the surface of LC double ceramic thermal barrier coating (LC/YSZ DCL-TBCs) and gradient thermal barrier coating (LC/YSZ FGM-TBCs) by flame spraying technology. The thermal shock resistance and failure mechanism of the coating samples were tested by thermal shock experiment at 1250 ℃. Scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) were used to track the location of CMAS and observe the thickness and morphology of CMAS and the reaction layer. X-ray diffractometer (XRD) was used to test the phase composition of the reaction layer and the coatings failure modes were summarized. The thermal shock results showed that the thermal shock life of the FGM-TBCs (435 times) was much higher than that of the DCL-TBCs (229 times), which was about 1.9 times longer than that of La2Ce2O7/YSZ DCL-TBCs. Both cerium lanthanum oxide layer and gradient layer could prevent CMAS from infiltrating into the coating to some extent and improve the thermal impact life under CMAS corrosion condition. The failure of two TBCs was mainly caused by layered spalling. The spalling layer were mainly the reaction layer of CMAS and LC, which generated refractory oxides such as Ca2(LaxCe1-x)8(SiO4)6O6-4x, fluorite phase and MgAl2O4, and the sintered layer under the reaction layer. This dense oxide layer was similar to the sealing layer and could prevent CMAS from further infiltration. The above results show that the FG-TBCs have better CMAS thermal shock resistance and better stress tolerance than the DCL-TBCs.