The work aims to investigate the change rules and mechanism on microstructure and properties of TiAlSiN coating after different thermal shock times. Arc ion plating was used to deposit TiAlSiN coating on the surface of monocrystalline silicon and M2 high-speed steel (W6Mo5Cr4V2) and thermal shock test was carried out by heating-water quenching cycle. The microstructure of the coating was characterized by 3D surface profilometer and scanning electron microscopy (SEM). Metallographic microscope was used to determine coating adhesion, EDS was used to analyze the change of coating element content, X-ray diffractometer (XRD) to characterize the phase structure and scratch tester and hardness tester to measure the mechanical properties of the coating. The tribological properties and mechanism of coatings were studied by friction wear tester and optical microscope. With the increase of thermal shock times, TiO particles produced on the surface of the coating became larger in size, content and roughness. The XRD peak shifted to small angle, but it was still cubic structure. The mechanical properties of the coating became worse, and the hardness value decreased from 2066HV0.025 to 1447HV0.025, the binding force decreased from 71.8 N to 33.9 N at room temperature, and the binding force level decreased from HF1 to HF4 at room temperature. In addition, after 30, 40, 50 thermal shock tests, the coating exhibited more excellent wear resistance than that at normal temperature and the friction coefficient decreased from 0.571 to 0.427, 0.389, 0.273. The wear rate decreased from 1.4×10-14 m3/(N?m) to 1.01×10-14 m3/(N?m), 0.93×10-14 m3/(N?m), 0.71×10-14 m3/(N?m) at room temperature and the main wear types were adhesive wear and oxidation wear. TiAlSiN coatings show excellent thermal shock resistance at 600 ℃ and can maintain cubic structure after repeated cold-heat cycles. With the increase of thermal shock times, the surface quality and mechanical properties of TiAlSiN coating decrease. However, in the friction and wear test, the coating surface has a lubricating effect due to the oxide formed by multiple thermal shocks, which effectively slows the violent contact between the coating and the friction ball and improves the wear resistance and friction reduction of TiAlSiN coatings significantly.