The work aims to improve the mechanical properties and tribological properties of Ni60A+Ti/MoS2 composite coating. La2O3 modified nickel-based self-lubricating composite coating was prepared on the surface of HT270 gray cast iron by laser cladding technology. The effects of La2O3 amount on microstructure, phase composition, microhardness and tribological properties at room temperature and 200 ℃ were analysed by hardness test, friction and wear test, XRD test and SEM. The La2O3 modified coating was mainly composed of CrNiFeC, NiTi, (Fe,Cr)7C3, Cr3C7, TiC, Ti2CS, MoS2 phases and La2O3. After La2O3 was added, the grains were refined and the structure was more uniform and dense. The microhardness and wear resistance of the cladding layer were improved. When the addition amount of La2O3 was 1.0%, the hardness of the coating was up to 776HV0.2. The tribological properties of the coating after La2O3 modification were also optimized. The 1.0% La2O3 coating had grinding loss of only 1.8 mg and friction coefficient of 0.48 at room temperature. Compared with the coating without La2O3, the weight loss was reduced by 47.1%, and the friction coefficient was also significantly reduced. The wear loss of 1.0% La2O3 coating was reduced by 41.3% and the friction coefficient was reduced to 0.50 at 200 ℃. The addition of La2O3 can effectively improve the tribological properties of the coating, such as wear reduction and wear resistance and also optimize the mechanical properties, such as the structure and hardness. La2O3 modified Ni-based coatings prepared by laser cladding can effectively improve the mechanical and tribological properties of composite coatings.