The work aims to compare the failure behavior of fluorocarbon coated plates after exposure in the atmospheric environment of Wenchang, Hainan and Xishuangbanna, Yunnan, and to explore the effects of mold on the aging behavior of flu-orocarbon coated plates. The surface morphology and protective performance of coating samples during different periods were monitored and analyzed by scanning electron microscopy (SEM), electrochemical impedance spectroscopy (EIS), and Fourier transform infrared spectroscopy (FT-IR). The aging failure and behavior of fluorocarbon coatings under the outdoor exposure of two different environments, Wenchang, Hainan and Xishuangbanna, Yunnan were explored. The SEM photographs showed that with the increase of the exposure time, the coating samples in both areas had different degrees of aging, and the surface of coating samples in Xishuangbanna showed obvious mold colony attachment. The results of EIS showed that compared with the samples in Wenchang, the low frequency impedance modulus of coatings in Xishuangbanna decreased rapidly. FT-IR results showed that the aging of the fluorocarbon coating in Xishuangbanna was mainly caused by the molecular chain breakage of the acrylic resin in the coating under the combined action of light and fungi and other microorganisms. In contrast, under the condition that the illumination time and radiation intensity were all higher than those in Xishuangbanna, samples in Wenchang exhibited better weather ability after atmospheric exposure. Therefore, the microbial degradation caused by the mold accelerates the photo-aging process of the coating and causes the serious aging of the sample exposed in Xishuangbanna.