The work aims to investigate the effect of the addition method of elemental powders V and Cr on the microstructure and formability of laser cladding deposited Ti-25V-15Cr alloy with Ti-25V-15Cr alloy as research subject. The deposition experiments were performed from three kinds of powder feedstock, including bonded coated Ti(150 mm)+V(15 mm)+Cr(15 mm), directly mixed Ti(150 mm)+V(15 mm)+Cr(15 mm) and directly mixed Ti(150 mm)+V(100 mm)+Cr(150 mm), and the height, width and microstructure of the deposited samples were analyzed. Deposited efficiency of the samples from the bonded coated Ti (150 mm)+V(15 mm)+Cr(15 mm) and directly mixed Ti(150 mm)+V(100 mm)+Cr(150 mm) were much higher than that from the directly mixed Ti(150 mm)+V(15 mm)+Cr(15 mm). The microstructure of the deposited samples from Ti(150 mm)+V(15 mm)+Cr(15 mm) and from directly mixed Ti(150 mm)+V(100 mm)+Cr(150 mm) were mainly composed of fine equiaxed grains and near-equiaxed grains, while that from the directly mixed Ti(150 mm)+V(15 mm)+Cr(15 mm) consisted of epitaxially columnar grains. When the bonded coated Ti (150 μm) + V (15 μm) + Cr (15 μm) is used as the deposited material, the grain size can be refined to some extent while the deposition efficiency can be improved. This method has a significant influence on the formability, composition uniformity and microstructure of the laser cladding deposited samples.