The work aims to study the effect of laser scanning speed on the microstructures and properties of laser cladding layers. The laser cladding Ni-based reinforced coatings were prepared by a TRUMPF Laser TruDisk 4002 fiber laser at the scanning speed of 300, 400 and 500 mm/min, respectively. The microstructure and phase composition of the laser cladding layers were analyzed by X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) and the microhardness and wear resistance of the cladding layers were tested by microhardness tester and friction wear tester. The microstructure of cladding layer was mainly composed of TiC, TiB2, Ti2Ni and γ-Ni. With the increase of scanning speed, the burning loss degree of Ti811 substrate decreased and the width W, height H, penetration of the substrate h and dilution rate λ also decreased gradually. When the scanning speed was 500 mm/min, the microstructure of the cladding layer was obviously refined and the average microhardness was up to 920HV0.5 which was 2 times of the microhardness of the substrate. When the scanning speed was 300, 400 and 500 mm/min, the average friction coefficient of the cladding layers was 0.45, 0.40 and 0.38 and the average wear mass loss was 2.1 mg, 1.7 mg and 1.4 mg. The Ni-based composite reinforced coatings can be successfully prepared by laser cladding technology on Ti811 alloy surface. The microstructure of cladding layer can be improved by selecting appropriate laser scanning speed. When the laser scanning speed is 500 mm/min, the grain size of the cladding layer is fine, the distribution of microstructure is dense and uniform and the microhardness and wear resistance are significantly increased.