The work aims to introduce basic properties, test and evaluation results as well as engineering application effect and direction of self-developed anti-abrasive self-lubricating fluoropolymer coating (referred to as synergistic coating). Properties of the coating were characterized with TOKYO SEIMITSU Surfcom gauge, SEM, electron probe line scanning analysis, microhardness tester, ball-disc wear tester, MM friction tester, Table friction-wear tester, CI4000 xenon lamp aging tester, FY-10E salt spray test chamber etc. Main applications of the synergistic coating were introduced by analyzing application examples. Coating thickness should be controlled between 20~60 μm, coating hardness on aluminum alloys should be 400~600HV, coating hardness on steel 700~950HV, coating friction coefficient below 0.15, wear loss below 50 mg/10 000 r, resistance to 5% neutral salt spray test over 336 h, and anti-ageing resistance 800 h. The coating still maintained prominent high temperature abhesion at 165 ℃. The coating exhibited outstanding comprehensive protective performance, hence it can meet requirements of single or overall functional protection including wear resistance, self-lubrication, corrosion resistance, temperature resistance and abhesion. The anti-abrasive self-lubricating fluoropolymer coating has integrated advantages of anodic oxide film or electroplated layer, and low friction fluoropolymer or lubricant featuring penetration control. Its large-scale application to steel and aluminum alloy materials shows that properties and technological state of the coating are stable, hence the coating is of extensive engineering application value.