The work aims to study effects of shot blasting forming and shot blasting strengthening on fatigue property of 2024HDT-T351 plate. A non-load transferring fatigue quality test piece of single detail structure with fastener was designed. Provided with same quantity of specimens and different shot blasting parameters, fatigue test was performed to test baseline group, shot blasting strengthening group, shot blasting forming group with 4 kinds of parameters and combined shot blasting forming & shot blasting strengthening group with 4 kinds of parameters. Fatigue properties, detail fatigue ratings and fatigue life under corresponding stress of all groups were obtained from fatigue test and by data processing. The detail fatigue ratings of all groups were higher than that of the test baseline group, fatigue property of shot blasting strengthening group increased by 24%; for the shot blasting forming group, by 9%~13%; and for the combined shot blasting forming & shot blasting strengthening group, by 9%~24%. The surface treatment coefficient B of 2024HDT-T351 subject to shot blasting forming and shot blasting strengthening for DFR analysis is given. The coefficient B of 2024HDT-T351 plate after shot blasting strengthening, after big shot blasting forming and after combined treatment can be taken as 1.2, 1.05 and 1.05.