Since nickel-base superalloy and titanium alloy feature in good high temperature strength, heat resistance, corrosion resistance and other excellent properties, they have been widely used in the field of aeronautics. However, these were typical difficult-to-machine materials of poor machinability, significant residual tensile stress could be easily generated on the machined surface, seriously affecting service life and performance of parts and components. It could obviously improve fatigue strength and corrosion resistance of the parts by adjusting and controlling the residual compressive stress. Compressive stress manufacturing technology, a typical antifatigue method, refers to a manufacturing technology aming to obtain residual compressive stress. Active control of residual compressive stress by combining ultrasonic technology compound with other processing methods was one of the main methods of antifatigue manufacturing technology. However, due to critical speed limit of ultrasonic machining, a few researches were carried out on ultrasonic and high speed composite manufacturing. However, both of them were the advanced manufacturing methods in compressive stress field. If the two methods could be integrated effectively, production of key parts could achieve higher efficiency while guaranteeing superior antifatigue performance. By the analyzing residual stress research progress of milling, high-speed machining and ultrasonic vibration machining, it was proposed that high speed machining and ultrasonic vibration machining could be combined in order to achieve efficient compressive stress manufacture of difficult-to-machine materials.