The work aims to study the corrosion behavior and mechanism of silver relics simulation materials which were exposed to ozone and LED lighting. Quartz crystal microbalance (QCM) and SEM-EDS were used to study the corrosion behavior and surface characteristics of silver relics simulation materials which were exposed to ozone and LED lighting. Frequency of silver-electrodeposited quartz crystal exposed to LED lighting or ozone decreased slightly, while that of silver-electrodeposited quartz crystal exposed to the compound condition of LED lighting and ozone decreased faster and more. Besides, the frequency of silver-electrodeposited quartz crystal decreased faster and more as color temperature of LED, ozone concentration or ambient temperature increased. Compared with light-free condition, more corrosion products and higher oxygen content were generated on the surface of silver exposed to LED lighting in an ozone environment with mass concentration of 5 μg/L. The higher the color temperature of LED lighting was, the more corrosion products were generated on the surface of silver. However, the production of corrosion products and the content of oxygen element on the surface of silver exposed to different brands of LED were similar. Ozone and LED lights will accelerate the corrosion of silver especially when the two coexist. The corrosion rate of silver increases with the increase of the LED color temperature, ozone concentration or ambient temperature while LED brands have similar influence on the silver corrosion.