With the rapid development of Bohai oilfield, CO2 corrosion becomes one of the key factors to hinder the development of oil and gas fields. Corrosion damage problem of tubing and casing caused by CO2 corrosion is becoming more and more serious in oil and gas wells, which has a serious influence on the working life of downhole tubing and restricts the “reducing costs and increasing benefits” development goals of Bohai oilfield. This paper reviewed CO2 corrosion mechanism of downhole tubing and its influencing factors, as well as the research status of anti-corrosion materials, summarized the corrosion situation of production wells for high oil and gas production blocks in Bohai oilfield, especially investigated CO2 partial pressure, temperature distribution and corrosion situation of production wells of SZ 36-1, CB and other 10 oilfields. Meanwhile, the influence laws of water medium, pH value, CO2 partial pressure on CO2 corrosion were discussed, and the results showed that carbon steel tubing had no serious corrosion when pCO2 <0.023 MPa; Corrosion damage rate of downhole tubing increased rapidly when pCO2 >0.2 MPa; Corrosion damage rate was about 19.15% when pCO2 was 0.3 MPa, which was in accordance with theoretical research. In the process of oil and gas development and production of Bohai oilfield, various factors might appear at the same time and interact with each other, which aggravated CO2 corrosion. The alloy element Cr could significantly increase the corrosion resistance of oil casing and tubing, and low Cr steels had good corrosion resistance and economy. The adaptability evaluation of low Cr casing and tubing in Bohai oilfield needs further research in the future.