Flue gas generated by the catalytic cracking regenerator is the main pollution source from oil refining enterprises. According to national environmental protection standards, flue gas desulfurization (FGD) plant must be used to control emissions of sulfur dioxide. FGD plant is in an extremely corrosive environment. Without effective protection measures, it will affect the safe and stable operation of the whole system. Because the corrosion-resistant alloy material for overall use in FGD is expensive, the nonmetallic material for linings is an important alternative. The article introduced several nonmetal linings in FGD device and their properties and application, including common nonmetal lining (rubber lining, glass resin flake lining, corrosion-resistant cement, corrosion-resistant brick lining, and whole fiberglass reinforced plastic) and novel high-performance anti-corrosion coatings ( polyurea and nanometer composite coatings, etc. ). Rubber lining has good chemical corrosion resistance and anti-permeability against media, but its temperature resistance is poor, so rubber lining is generally used in the region of large mechanical load and at low temperatures, such as internal part of absorption tower, slurry system and low-temperature flue. Glass flake resin lining has favorably comprehensive performance, which is widely applied in various areas of the flue gas desulfurization device, such as the flue, the absorption tower and so on. FRP lining is often used in pipeline of the desulfurization system and spray pipe in the absorption tower and other sites. Corrosion-resistant cement and brick lining are the earlier applied anti-corrosion technologies with poorer impact resistance compared with other non-metallic linings. Polyurea and nanometer composite coating are heavy-duty coatings and new technologies for protection of FGD equipment from corrosion. Even though they have some applications in the refinery desulfurization device, their performance remains to be proved.