Objective To study the resistance of Cobalt-based alloy- stainless steel gradient reinforcement materials against lowstress multi-touch plastic deformation, in order to improve the stress concentration problem of single coating. Methods The samples were prepared by laser cladding Cobalt-based alloy powder with exponential and linear weight fraction on substrates. Low-stress multi-touch experiment was conducted against the 304 stainless steel substrate. The plastic deformation, hardness and microstructure of all coatings were analyzed and compared in details. Results The cumulative plastic deformation of the sample with addition of linear gradient weight fraction Cobalt-based alloy powder was reduced by about 50% compared to the 304 stainless steel substrate, while the cumulative plastic deformation of the sample with addition of exponential gradient weight fraction Cobalt-based alloy powder was reduced by about 67% compared to the 304 stainless steel substrate. Although cyclic hardening and cyclic softening phenomena existed in both Cobalt-based gradient reinforced samples, the overall variation trend of the micro-hardness was that micro-hardness values gradually decreased from the surface to the substrate. Besides, the plastic deformation of reinforced materials conformed to " skin effect" after multi-touch. Conclusion The resistance of both gradient reinforced coatings against low-stress multi-touch plastic deformation was much better than that of the substrate without reinforcement, and the properties of exponential gradient reinforced samples were better than those of the linear reinforced samples.