激光-化学复合调控&#x003b2;钛合金超疏水表面

王申奥; 付秀丽; 孟莹; 潘永智; 宋淑勤; 门秀花

doi:10.16490/j.cnki.issn.1001-3660.2026.10.017

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表面技术 ›› 2026, Vol. 55 ›› Issue (10) : 208-222. DOI: 10.16490/j.cnki.issn.1001-3660.2026.10.017

功能表面及技术

激光-化学复合调控β钛合金超疏水表面

王申奥¹, 付秀丽^1,2,*, 孟莹¹, 潘永智¹, 宋淑勤¹, 门秀花¹

作者信息 +

Laser-chemical Composite Regulation of the Superhydrophobic Surface of β Titanium Alloys

WANG Shenao¹, FU Xiuli^1,2,*, MENG Ying¹, PAN Yongzhi¹, SONG Shuqin¹, MEN Xiuhua¹

Author information +

文章历史 +

摘要

目的钛合金因其优异的性能在生物医疗领域备受关注,然而,当钛合金表面与血液接触时,可能导致血栓的形成,本研究针对钛合金在生物医疗应用中易诱发血栓的问题,提出通过构建超疏水表面以改善其血液相容性。方法以β钛合金TB9为研究对象,采用飞秒激光在其表面制备微织构,并结合化学修饰降低表面自由能。利用扫描电子显微镜和激光共聚焦显微镜系统分析不同激光参数对表面烧蚀形貌及织构尺寸的影响,通过接触角测量评估其润湿性能,并借助X射线光电子能谱、傅里叶变换红外光谱及拉曼光谱对表面化学组成进行表征。同时,通过线性摩擦试验评价表面的机械耐久性,并开展溶血率及血小板黏附试验以评估其血液相容性。结果通过优化激光参数与化学修饰,可成功构建具有164.2°水接触角和1.8°滚动角的超疏水表面。该表面表现出优异的抗血液黏附性能,其超疏水特性来源于表面微织构与低表面能物质的协同作用。化学分析结果证实氟硅烷成功修饰于TB9表面。耐久性测试表明,该超疏水表面在20个摩擦周期后仍能保持超疏水状态。超疏水表面的溶血率为0.248 1%,满足医用材料直接接触血液的要求,且血小板黏附试验表明,超疏水表面未观察到明显的血小板黏附。结论通过飞秒激光与化学改性相结合的方法,在TB9钛合金表面成功构建了稳定的超疏水结构,为其在生物医疗领域的应用提供了一种简便且低成本的可行途径。

Abstract

Titanium alloys have attracted extensive attention in the biomedical field due to their outstanding properties, including high specific strength, excellent corrosion resistance, and good biocompatibility. However, when titanium alloy surfaces come into direct contact with blood, they may induce thrombus formation, which significantly limits their clinical applications. To address this issue, the work aims to propose the construction of a superhydrophobic surface to improve the hemocompatibility of titanium alloys and reduce the risk of thrombosis during implantation. In this work, a β titanium alloy TB9 was selected as the substrate material. Femtosecond laser processing was employed to fabricate micro-scale surface textures on the TB9 alloy, followed by chemical modification to reduce the surface free energy. The effects of different laser processing parameters on surface ablation morphology and texture dimensions were systematically investigated through scanning electron microscopy (SEM) and laser confocal microscopy. To achieve superhydrophobicity, the sample surfaces underwent chemical modification to reduce surface energy. The laser-etched samples were immersed in a 2wt.% solution of 1H,1H,2H,2H- Perfluorodecyltrimethoxysilane (FAS-17) at room temperature for 2 hours, followed by thermal curing in a constant temperature drying oven at 120 ℃ for 120 minutes. The wettability of the processed surfaces was evaluated by contact angle measurements under varying processing conditions. Furthermore, the surface chemical composition and functional groups were characterized with X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR), and Raman spectroscopy to confirm the successful chemical modification. To assess the durability of the fabricated superhydrophobic surface, linear friction tests were conducted to evaluate its mechanical robustness. In addition, hemolysis tests and platelet adhesion experiments were performed to investigate the hemocompatibility of the modified surfaces. The results demonstrated that by optimizing the femtosecond laser parameters and combining them with appropriate chemical modification, a stable superhydrophobic surface was successfully fabricated on the TB9 titanium alloy. The obtained surface exhibited a water contact angle of up to 164.2° and a low sliding angle of 1.8°, indicating excellent water repellency. The superhydrophobic surface also showed remarkable anti-blood adhesion performance. The wettability analysis revealed that the formation of the superhydrophobic state was attributed to the synergistic effect between the hierarchical microstructures generated by laser ablation and the low surface energy materials introduced during chemical modification. Surface chemical characterization confirmed that fluorosilane molecules were successfully deposited onto the TB9 substrate, contributing to the reduced surface energy. The durability tests indicated that the superhydrophobic surface maintained its water-repellent properties even after 20 cycles of linear friction, demonstrating good mechanical stability. The hemolysis rate of the superhydrophobic surface was measured to be 0.248 1%, which met the requirements for biomedical materials in direct contact with blood. Moreover, the platelet adhesion experiments showed that there was no significant platelet attachment observed on the superhydrophobic surface, indicating excellent resistance to platelet adhesion and activation. In summary, a robust and stable superhydrophobic surface is successfully fabricated on TB9 titanium alloy through a combination of femtosecond laser ablation and chemical modification. The prepared surface not only exhibits excellent wettability and mechanical durability but also significantly improves hemocompatibility by reducing hemolysis and inhibiting platelet adhesion. This work provides a simple, efficient, and low-cost strategy for constructing superhydrophobic surfaces on titanium alloys, thereby expanding their potential applications in the biomedical field, particularly for blood-contacting implants and devices.

导出引用

王申奥, 付秀丽, 孟莹, 潘永智, 宋淑勤, 门秀花. 激光-化学复合调控β钛合金超疏水表面[J]. 表面技术. 2026, 55(10): 208-222

WANG Shenao, FU Xiuli, MENG Ying, PAN Yongzhi, SONG Shuqin, MEN Xiuhua. Laser-chemical Composite Regulation of the Superhydrophobic Surface of β Titanium Alloys[J]. Surface Technology. 2026, 55(10): 208-222

中图分类号： TG178

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