医用镁及镁合金过快的降解速率严重缩短了其有效服役时间，过高的析氢速率引发局部炎症，束缚了其临床应用前景。微弧氧化(MAO)/有机复合涂层良好的抑蚀降析性能，在医用镁及镁合金表面改性领域展现出巨大的应用潜力。首先，从有机材料(植酸(PA)、壳聚糖(CS)、硬脂酸(SA)、多巴胺(DA)、聚乳酸-乙醇酸共聚物(PLGA)、聚乳酸(PLA)、聚已内酯(PCL))自身的组织及性能特征入手，分析了单一有机涂层提高镁及镁合金耐蚀性的作用机理，并指出单一涂层自身的性能弱点(单一MAO涂层微孔和裂纹的不可避免，单一有机涂层与镁合金结合强度低，易于剥落)限制了对镁合金降解保护效能。其次，从结合强度、耐蚀性、多功能性(生物安全性、生物相容性、诱导再生性、抑菌抗菌性、载药缓释性等)的角度，详细阐述了各MAO/有机复合涂层的结构特点、优势特征。在此基础上，明确指出以MAO/PCL(MAO/CS)复合涂层为基底涂层，通过PCL(CS)涂层与其他涂层的交叉组合，是实现医用镁合金植入材料的生物活性及多功能性的最佳路径。最后，对镁合金MAO/有机复合涂层的演进方向进行了科学展望。

Good biosafety, biocompatibility and valuable self-degradation properties endow medical magnesium and magnesium alloys with great potential to replace inert implant materials in the field of traditional clinical applications. The excessive degradation rate of magnesium alloy, however, leads to its premature loss of structural integrity and mechanical support, being unable to complete the effective service time necessary for tissue healing of the implant site. At the same time, it is also its excessive degradation rate that leads to the intensification of hydrogen evolution reaction of magnesium alloy. Because it cannot be absorbed by the human body in a short time, the excessive H2 will easily gather around the implant or form a subcutaneous airbag, which will not only cause the inflammation of the implant site, but also hinder the adhesion and growth of cells in the implant, limiting its clinical application prospects. Surface modification technology can effectively delay the degradation rate of medical magnesium and magnesium alloys, and reduce the rate of hydrogen evolution.