唾液蛋白的吸附与润滑行为研究进展

曾启航, 唐悦, 周均, 郑靖, 周仲荣

表面技术 ›› 2020, Vol. 49 ›› Issue (6) : 85-91.

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PDF(2337 KB)
表面技术 ›› 2020, Vol. 49 ›› Issue (6) : 85-91. DOI: 10.16490/j.cnki.issn.1001-3660.2020.06.010
研究综述

唾液蛋白的吸附与润滑行为研究进展

  • 曾启航1, 唐悦2, 郑靖2, 周仲荣2, 周均3
作者信息 +

Research Advance in Adsorption and Lubrication Behaviors of Salivary Proteins

  • ZENG Qi-hang1, TANG Yue2, ZHENG Jing2, ZHOU Zhong-rong2, ZHOU Jun3
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文章历史 +

摘要

首先针对唾液蛋白的吸附行为,介绍了唾液蛋白吸附膜的多层膜结构,分析了唾液蛋白在牙齿表面的选择性吸附机制,指出口腔内的唾液蛋白通过静电作用吸附于牙釉质表面形成初始膜,唾液蛋白之间通过氢键和范德华力吸附形成外层膜,并归纳总结了唾液蛋白种类、吸附时间、基体种类和口腔环境等因素对唾液蛋白吸附与成膜行为的影响。在此基础上,进一步介绍了唾液蛋白吸附膜的边界润滑行为,以及唾液膜成分、基体表面亲疏水性和口腔环境等因素对唾液膜边界润滑行为的影响规律,并对唾液蛋白吸附膜润滑性能的宏微观测试手段进行了归纳总结。最后,分析讨论了现阶段唾液蛋白吸附行为和润滑行为研究中存在的不足以及未来的发展趋势。

Abstract

First, in allusion to the adsorption behavior of salivary protein, this paper introduced the multi-layer structure of salivary pellicle and analyzed the selective adsorption mechanism of salivary protein on the tooth surface. It was pointed out that the intraoral salivary proteins can be adsorbed on the tooth surface by electrostatic interaction to form the initial inner layer upon which the outer layer is formed by hydrogen bonds and van der Waals forces among proteins. And then the main influencing factors of the adsorption and film-forming behavior of salivary proteins were illustrated, including protein type, adsorption time, substrate type and oral environment factors. On this basis, the boundary lubrication behavior of the salivary pellicle, as well as the influence of the salivary pellicle composition, the surface hydrophobicity/hydrophilicity and the oral environment on this boundary lubrication were introduced. Also, the macroscopic/microscopic testing methods of the lubrication performance of salivary pellicle were summarized. Finally, the shortcomings and future development trends of the adsorption behavior and lubrication behavior research of saliva proteins were discussed.

关键词

唾液蛋白;基体;生物膜;吸附机制;润滑行为

Key words

salivary protein; substrate; biofilm; adsorption mechanism; lubrication behavior

引用本文

导出引用
曾启航, 唐悦, 周均, 郑靖, 周仲荣. 唾液蛋白的吸附与润滑行为研究进展[J]. 表面技术. 2020, 49(6): 85-91
ZENG Qi-hang, TANG Yue, ZHOU Jun, ZHENG Jing, ZHOU Zhong-rong. Research Advance in Adsorption and Lubrication Behaviors of Salivary Proteins[J]. Surface Technology. 2020, 49(6): 85-91

基金

国家自然科学基金项目(51675449,51535010)

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