结合文献和课题组的研究，对医用金属材料腐蚀疲劳性能的研究进展进行了总结，分别从腐蚀疲劳的危害性、分类、设计、控制等几个方面进行了阐述。腐蚀疲劳失效首先发生于材料表面，医用材料-生理环境的界面对于植入器械手术成功与否有着至关重要的作用，可以根据裂纹扩展速度曲线特征，将腐蚀疲劳分为三类。医用金属材料的腐蚀疲劳性能研究应考量其服役环境进行设计，可以通过表面处理、合金化等方法改善医用金属材料的腐蚀疲劳性能。医用金属材料腐蚀疲劳性能研究的一些基础问题仍待解决：医用金属材料在微生物参与下的腐蚀疲劳行为及其相关机制亟待阐述；医用金属材料的微生物腐蚀疲劳研究是一个系统、长期、复杂的过程，需要合理地建立实验模型，将三维有限元与传统实验方法有机结合，进一步指导医用金属材料相关器械的设计；新的合金成分设计、新的加工制造方式所获得的新型合金生理环境下的腐蚀疲劳性能，其相关数据亟待完善，这关系到新型医用金属材料长期使用的生物安全性问题，亟需开展大量的基础研究工作。在综合评述医用金属材料腐蚀疲劳性能研究现状的基础上，对医用金属腐蚀疲劳在学科交叉研究和新材料基础研究方面的发展趋势进行了展望。

The corrosion fatigue of biomedical metallic alloys were summarized. This paper summarized the harmfulness, classification, design and control of the corrosion fatigue of biomedical metals for medical application. The current research status of the corrosion fatigue of biomedical metals were reviewed, and the future research and development in interdisciplinary research and new materials of the corrosion fatigue were proposed. Corrosion fatigue usually initiated from the surface which was relative with the lifespan of the implants. The corrosion fatigue was distributed into three types. Environment should be considered for the design of the research of corrosion fatigue study. Surface modification and alloying can be used to improve the corrosion fatigue properties of the metals. Many problems need to be solved. The corrosion fatigue behavior and the mechanism of microbiologically influenced corrosion should be elucidated. Microbiologically influenced corrosion fatigue is a long and complex process. The rea-sonable three-dimensional finite element dynamical analysis models should be combined with the experiments to guide the design of implants. The fundamental data especially the corrosion fatigue related data of many new alloys is still unknown. Much work should be done to ensure the safety of the new metals in service.