目的 模拟生活中不粘锅的使用环境，采用响应面法预测铁表面PTFE涂层的使用寿命，为生活中合理使用不粘锅提供支撑。方法 通过响应面法考察转速和载荷对铁表面PTFE涂层使用寿命的影响，采用中心组合试验设计（CCD）考察载荷以及转速对于铁表面PTFE涂层使用寿命的影响及其相互作用。结果 载荷和转速对于涂层使用寿命的影响都极为显著，检验值（F）都小于0.0001。通过试验设计软件得出使用寿命与转速和载荷的二阶多项式方程，并且复相关系数R2为0.9951，能解释99.51%响应值的变化，因此模型能够较准确地预测铁表面PTFE涂层的使用寿命。该实验工况下铁表面PTFE涂层的最佳使用参数分别为转速200 r/min和载荷25 N，此时涂层寿命为147 min左右。结论 模拟日常生活中使用不粘锅的实际情况，并运用响应面法分析和预测PTFE涂层的使用寿命具有科学性和可操作性，能够很好地指导生活中安全使用不粘锅。

The work aims to predict service life of PTFE coating on iron surface to provide basis for using non-stick pan reasonably by simulating service environment of non-stick pan in daily life. The response surface methodology was used to explore the effects of revolving speed and load on service life of PTFE coating on iron surface. Central composite design (CCD) was used to analyze the effects of revolving speed and load on the service life of PTFE coating on iron surface as well as their interactions. Load and revolving speed both had significant effects on service life of the coating. The test values (F) were all less than 0.0001. A second-order polynomial equation involving service life, speed and load was established by using a test design software. Multiple correlation coefficient was 0.9951, which could explain why response value changed to be 99.51%. Therefore, the model could accurately predict the service life of PTFE coating on iron surface. The optimum applied parameters of the coating were: load as 25 N and revolving speed as 200 r/mim. The expected service life of the coating was about 147 min. It is scientific and reliable to study the service life of PTFE coating by using response surface methodology and simulating practical situation with non-stick pan. It can provide effective guidance for safe use of non-stick pan in daily life.