LIU Yi,SUO Xin-kun,HUANG Jing,NIINOMI Mitsuo,LI Hua.Applications and Perspectives of Cold Spray Technique in Biomedical En-gineering: A Review[J],45(9):25-31 |
Applications and Perspectives of Cold Spray Technique in Biomedical En-gineering: A Review |
Received:April 18, 2016 Revised:September 20, 2016 |
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DOI:10.16490/j.cnki.issn.1001-3660.2016.09.004 |
KeyWord:cold spray biological application biomaterials biological properties |
Author | Institution |
LIU Yi |
Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo , China |
SUO Xin-kun |
Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo , China |
HUANG Jing |
Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo , China |
NIINOMI Mitsuo |
Department of Biomaterial Science, Institute for Materials Research, Tohoku University, Sendai 980-8577, Japan |
LI Hua |
Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo , China |
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Abstract: |
High temperature during coating deposition is still the major hurdle that impedes its application for processing temperature-sensitive, oxygen-sensitive or specially designed materials. Cold spray is an emerging coating technique that offers unique and distinctive coating characteristics, and biocompatible metallic materials (Ti- Fe- Co- and Mg-based alloys), polymers (UHMWPE, HDPE, PEEK) and some ceramics (HA, HA-graphene, TiO2) have been successfully deposited by cold spray processing for tissue engineering and anti-bacterial applications. For cold sprayed biomedical coatings, extensive knowledge has been gained pertaining to fundamental issues about material selection, coating processing, dynamic coating formation, biological performances, and microstructure-property relations. While some of the biomedical coatings are still in the preclinical testing stage. Knowledge on in vitro and in vivo behaviors of cold sprayed biomedical coatings at different levels is yet insufficient. This review also provides future perspectives of the promising cold spray technique for fabricating advanced biomedical coatings and 3D printing for making biomedical devices. |
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