| ZHOU Chang-chun,YE Xing-jiang,XIAO Zhan-wen,WANG Zhe,ZHANG Xing-dong.Micro / Nano-modification of Calcium Phosphate Bone Tissue Engineering Scaffold[J],43(4):82-85 |
| Micro / Nano-modification of Calcium Phosphate Bone Tissue Engineering Scaffold |
| Received:March 04, 2014 Revised:May 05, 2014 |
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| DOI： |
| KeyWord:bone tissue engineering scaffolds porous calcium phosphate ceramics hydrothermal method whisker surface micro / nano-modification |
| Author | Institution |
| ZHOU Chang-chun |
National Engineering Research Center for Biomaterials, Sichuan University, Chengdu , China |
| YE Xing-jiang |
National Engineering Research Center for Biomaterials, Sichuan University, Chengdu , China |
| XIAO Zhan-wen |
National Engineering Research Center for Biomaterials, Sichuan University, Chengdu , China |
| WANG Zhe |
National Engineering Research Center for Biomaterials, Sichuan University, Chengdu , China |
| ZHANG Xing-dong |
National Engineering Research Center for Biomaterials, Sichuan University, Chengdu , China |
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| Abstract: |
| Objective To research the surface micro / nano-modification of porous calcium phosphate bone tissue engineering scaffolds. Methods Porous calcium phosphate bone tissue engineering scaffolds were prepared by the H2 O2 foaming method. Then the hydrothermal method was applied for the surface micro / nano-modification. The scanning electron microscopy ( SEM) was used for microstructure observations, and the X-ray diffraction ( XRD) was used to analyze the phase composition of the modified layer. Results After the surface modification, scaffolds with a total porosity of ( 63 ± 8 ) % , and a pore size of ( 310 ± 30 ) μm were obtained. The modified surface layers were hydroxyapatite nanocrystals or whiskers, the length of whisker ranged 20 ~ 40 μm, and the diameter was in range of 100 ~ 300 nm. Conclusion The inner and outer surfaces of porous calcium phosphate scaffolds formed a micro / nano-modification layer by hydrothermal treatment. The performance of the material was improved. KEY WORDS: |
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