| YANG Xiaofeng,ZHANG Hao,SHEN Xiaolong,FAN Xingping,WANG Haibo,YANG Cheng,WANG Binbin,CHENG Bo,LI Xiaojie,YANG Jing.Preparation and Research of pH-Responsive Antibacterial Coatings Based on Polyphenol-silver Complexes[J],53(23):121-130 |
| Preparation and Research of pH-Responsive Antibacterial Coatings Based on Polyphenol-silver Complexes |
| Received:May 20, 2024 Revised:October 14, 2024 |
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| DOI：10.16490/j.cnki.issn.1001-3660.2024.23.010 |
| KeyWord:biomedical titanium titanium dioxide polydopamine gallic acid silver ion pH response |
| Author | Institution |
| YANG Xiaofeng |
College of Vanadium and Titanium, Sichuan Panzhihua , China |
| ZHANG Hao |
College of Vanadium and Titanium, Sichuan Panzhihua , China ;Vanadium and Titanium Resource Comprehensive Utilization Key Laboratory of Sichuan Province, Sichuan Panzhihua , China |
| SHEN Xiaolong |
College of Biology and Chemical Engineering, Panzhihua University, Sichuan Panzhihua , China |
| FAN Xingping |
College of Vanadium and Titanium, Sichuan Panzhihua , China |
| WANG Haibo |
College of Vanadium and Titanium, Sichuan Panzhihua , China |
| YANG Cheng |
College of Vanadium and Titanium, Sichuan Panzhihua , China |
| WANG Binbin |
College of Vanadium and Titanium, Sichuan Panzhihua , China |
| CHENG Bo |
College of Vanadium and Titanium, Sichuan Panzhihua , China |
| LI Xiaojie |
College of Vanadium and Titanium, Sichuan Panzhihua , China |
| YANG Jing |
College of Vanadium and Titanium, Sichuan Panzhihua , China |
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| Abstract: |
| Titanium and titanium alloys have a wide range of clinical applications in dental implants, bone screws, and artificial hip joints. However, due to their biological inertia and lack of antibacterial properties, excellent osseointegration cannot be achieved after surgery, they are prone to bacterial infection, inflammation, and implant failure. Surface modification can effectively endow it with biological functions such as promoting bone growth, antibacterial and anti-inflammatory. In view of the bacterial infection of the implant, according to the low pH value of the surrounding environment of the infected tissue, the construction of pH-responsive antibacterial function on the surface of the implant has become a research hotspot. In this study, metal-polyphenol network (MPN) was used to graft silver ions in TiO2 (titanium dioxide) nanotubes, and the responsive release of silver ions was achieved by the pH responsiveness of MPN. |
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