胡怡娟,毕衍泽,何东磊,于宏燕,李岩.可生物降解镁及镁合金表面改性研究进展[J].表面技术,2019,48(9):11-19.
HU Yi-juan,BI Yan-ze,HE Dong-lei,YU Hong-yan,LI Yan.Research Progress on Surface Modification of Biodegradable Magnesium and Magnesium Alloys[J].Surface Technology,2019,48(9):11-19
可生物降解镁及镁合金表面改性研究进展
Research Progress on Surface Modification of Biodegradable Magnesium and Magnesium Alloys
投稿时间:2019-04-16  修订日期:2019-09-20
DOI:10.16490/j.cnki.issn.1001-3660.2019.09.002
中文关键词:  可生物降解镁及镁合金  表面改性  涂层  降解速率
英文关键词:biodegradable magnesium and magnesium alloy  surface modification  coating  degradation rate
基金项目:北京市自然科学基金(2182021)
作者单位
胡怡娟 1.北京航空航天大学 a.材料科学与工程学院 b.生物医学工程高精尖创新中心,北京 100191 
毕衍泽 1.北京航空航天大学 a.材料科学与工程学院 b.生物医学工程高精尖创新中心,北京 100191 
何东磊 1.北京航空航天大学 a.材料科学与工程学院 b.生物医学工程高精尖创新中心,北京 100191 
于宏燕 2.北京市射线应用研究中心 辐射新材料北京市重点实验室,北京 100015 
李岩 1.北京航空航天大学 a.材料科学与工程学院 b.生物医学工程高精尖创新中心,北京 100191 
AuthorInstitution
HU Yi-juan 1.a.School of Material Science and Engineering, b.Beijing Advanced Innovation Center for Biomedical Engineering, Beijing University of Aeronautics and Astronautics, Beijing 100191, China 
BI Yan-ze 1.a.School of Material Science and Engineering, b.Beijing Advanced Innovation Center for Biomedical Engineering, Beijing University of Aeronautics and Astronautics, Beijing 100191, China 
HE Dong-lei 1.a.School of Material Science and Engineering, b.Beijing Advanced Innovation Center for Biomedical Engineering, Beijing University of Aeronautics and Astronautics, Beijing 100191, China 
YU Hong-yan 2.Beijing Key Laboratory of Radiation Advanced Materials, Beijing Research Center for Radiation Application, Beijing 100015, China 
LI Yan 1.a.School of Material Science and Engineering, b.Beijing Advanced Innovation Center for Biomedical Engineering, Beijing University of Aeronautics and Astronautics, Beijing 100191, China 
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中文摘要:
      生物医用镁及镁合金可降解吸收,具有良好的生物相容性,弹性模量与人体骨接近,是理想的人体植入物材料。在体液环境中,医用镁合金腐蚀速率较快,常常导致植入物过早失效。对镁合金表面进行适当改性,可调控合金降解速率、提高生物相容性。最常见的表面改性方法是在镁合金表面生成保护性涂层,这些涂层主要包括可降解高分子涂层和一些无机涂层。综述了近几年可生物降解镁及镁合金的表面改性涂层及改性技术的最新研究动态,探讨了镁及镁合金表面制备无机涂层和可降解高分子涂层的一些改性方法;简要介绍了阳极氧化、微弧氧化、离子注入、溶胶-凝胶、等离子喷涂及化学沉积等表面改性方法的原理,并比较其优缺点;提出了可生物降解镁及镁合金表面改性涂层研究中面临的问题,并展望了未来发展方向。
英文摘要:
      Medical magnesium and magnesium alloys with good biocompatibility can be absorbed and degraded. Due to the elastic modulus close to that of human bone, medical magnesium and magnesium alloys can effectively alleviate the stress shielding effect, thus becoming ideal body implant materials. In body fluids, the medical magnesium alloys often lead to premature failure of the implant due to faster corrosion rate. Therefore, appropriate surface modification is carried out on magnesium alloy to control the alloy degradation rate and improve biocompatibility. A variety of biodegradable magnesium and magnesium alloy surface modification technologies have been developed for different applications and performance requirements. The most common is the formation of a protective coating on the surface of the magnesium alloy to reduce the direct contact between magnesium and corrosive environments, thereby reducing the corrosion rate. These coatings mainly include degradable polymer coatings and some inorganic coatings. The latest research trends of surface-modified coatings and modification techniques of degradable magnesium alloys in recent years were reviewed, and the modification methods of degradable polymer coatings and inorganic coatings prepared on magnesium and magnesium alloys were explored. The principles of surface modification methods such as anodizing, micro-arc oxidation, ion implantation, sol-gel, plasma spraying, chemical deposition, etc. were briefly introduced and advantages and disadvantages were compared. Finally, the problems of the surface modification coating of degradable magnesium and magnesium alloys in clinical application were put forward and the future development direction was expected.
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