曾启航,唐悦,周均,郑靖,周仲荣.唾液蛋白的吸附与润滑行为研究进展[J].表面技术,2020,49(6):85-91.
ZENG Qi-hang,TANG Yue,ZHOU Jun,ZHENG Jing,ZHOU Zhong-rong.Research Advance in Adsorption and Lubrication Behaviors of Salivary Proteins[J].Surface Technology,2020,49(6):85-91
唾液蛋白的吸附与润滑行为研究进展
Research Advance in Adsorption and Lubrication Behaviors of Salivary Proteins
投稿时间:2019-10-12  修订日期:2020-06-20
DOI:10.16490/j.cnki.issn.1001-3660.2020.06.010
中文关键词:  唾液蛋白  基体  生物膜  吸附机制  润滑行为
英文关键词:salivary protein  substrate  biofilm  adsorption mechanism  lubrication behavior
基金项目:国家自然科学基金项目(51675449,51535010)
作者单位
曾启航 1. 西南交通大学 摩擦学研究所,成都 610031;2. 重庆文理学院 智能制造工程学院,重庆 402160 
唐悦 1. 西南交通大学 摩擦学研究所,成都 610031 
周均 3. 浙江省医疗器械检验研究院,杭州 310018 
郑靖 1. 西南交通大学 摩擦学研究所,成都 610031 
周仲荣 1. 西南交通大学 摩擦学研究所,成都 610031 
AuthorInstitution
ZENG Qi-hang 1.Tribology Research Institute, Southwest Jiaotong University, Chengdu 610031, China; 2.School of Intelligent Manufacturing Engineering, Chongqing University of Arts and Sciences, Chongqing 402160, China 
TANG Yue 1.Tribology Research Institute, Southwest Jiaotong University, Chengdu 610031, China 
ZHOU Jun 3.Zhejiang Institute for the Control of Medical Device, Hangzhou 310018, China 
ZHENG Jing 1.Tribology Research Institute, Southwest Jiaotong University, Chengdu 610031, China 
ZHOU Zhong-rong 1.Tribology Research Institute, Southwest Jiaotong University, Chengdu 610031, China 
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中文摘要:
      首先针对唾液蛋白的吸附行为,介绍了唾液蛋白吸附膜的多层膜结构,分析了唾液蛋白在牙齿表面的选择性吸附机制,指出口腔内的唾液蛋白通过静电作用吸附于牙釉质表面形成初始膜,唾液蛋白之间通过氢键和范德华力吸附形成外层膜,并归纳总结了唾液蛋白种类、吸附时间、基体种类和口腔环境等因素对唾液蛋白吸附与成膜行为的影响。在此基础上,进一步介绍了唾液蛋白吸附膜的边界润滑行为,以及唾液膜成分、基体表面亲疏水性和口腔环境等因素对唾液膜边界润滑行为的影响规律,并对唾液蛋白吸附膜润滑性能的宏微观测试手段进行了归纳总结。最后,分析讨论了现阶段唾液蛋白吸附行为和润滑行为研究中存在的不足以及未来的发展趋势。
英文摘要:
      First, in allusion to the adsorption behavior of salivary protein, this paper introduced the multi-layer structure of salivary pellicle and analyzed the selective adsorption mechanism of salivary protein on the tooth surface. It was pointed out that the intraoral salivary proteins can be adsorbed on the tooth surface by electrostatic interaction to form the initial inner layer upon which the outer layer is formed by hydrogen bonds and van der Waals forces among proteins. And then the main influencing factors of the adsorption and film-forming behavior of salivary proteins were illustrated, including protein type, adsorption time, substrate type and oral environment factors. On this basis, the boundary lubrication behavior of the salivary pellicle, as well as the influence of the salivary pellicle composition, the surface hydrophobicity/hydrophilicity and the oral environment on this boundary lubrication were introduced. Also, the macroscopic/microscopic testing methods of the lubrication performance of salivary pellicle were summarized. Finally, the shortcomings and future development trends of the adsorption behavior and lubrication behavior research of saliva proteins were discussed.
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